Do Collagen Peptides benefit your skin, nails, and joints? Are there any clinical studies to back up these claims?

Interested in Collagen Peptides but worried that the benefits sound too good to be true? 😬🤞

Good news! Collagen Peptides really do benefit your skin, nails, and joints, but don't just take our word for it!

Collagen Peptides and Skin Health

In two placebo-controlled clinical trials designed to assess the effects of daily oral collagen peptides supplementation, researchers found a significant increase in skin hydration after 8 weeks of intake. Using high-resolution ultrasound and skin biopsies, they were able to determine that skin collagen density was also significantly increased, collagen fragmentation (damage) was decreased and production of glycosaminoglycans (such as hyaluronic acid) was also increased. These findings led the researchers to conclude that, "The oral supplementation with collagen peptides is efficacious to improve hallmarks of skin aging."

A separate double-blind, placebo-controlled trial, 69 women aged 35-55 years received either 2.5g collagen hydrolysate (hydrolyzed collagen peptides), 5g collagen hydrolysate, or a placebo. After four weeks, both of the collagen hydrolysate groups showed a statistically significant improvement in skin elasticity, improvements in skin moisture, and none reported side effects.

A third study looked at collagen peptides ability to combat cellulite specifically by giving 2.5g bioactive collagen peptides to 105 women aged 24-50 years for a 6 month period. At the end of the study period, statistically significant improvements thigh cellulite in normal-weight participants and improvement (but not to a statistically significant degree) in thigh cellulite in overweight participants. Overall, the researchers concluded that long term, oral intake of bioactive collagen peptides "leads to an improvement of cellulite and has a positive impact on skin health."


1) The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials

2) Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study.

3) Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology

Collagen Peptides and Nail Health

In a study of 25 participants who received 2.5g of bioactive collagen peptides once a day for 24 weeks, researchers found that participants experience a 42% decrease in broken nail frequency and a 12% increase in nail growth. They also found that 64% of participants saw a clinical improvement in brittle nails and 88% of participants continued to experience improvements in nail health 4 weeks post-treatment. These results led to the conclusion that "Daily ingestion of (bioactive collagen peptides) increased nail growth and improved brittle nails in conjunction with a notable decrease in the frequency of broken nails."


1) Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.

Collagen Peptides and Joint Health

A double-blind, placebo-controlled, and randomized trial was conducted to determine if collagen peptides could help patients with diagnosed knee osteo-arthritis. After 13 weeks of treatment with either bovine bone collagen peptides, pork skin collagen peptides, or a placebo, the patients were assessed in order to see if they experienced any changes in joint range of motion and overall quality of life. The researchers found that both collagen groups had significant improvements in pain, stiffness, and functional movement while the placebo group did not see any such changes. This led to the conclusion that "collagen peptides are potential therapeutic agents as nutritional supplements for the management of osteoarthritis and maintenance of joint health."

In a study focussing on athletes, researchers randomly assigned two groups of subjects (147 total) to receive either 10g of collagen peptides or xanthan gum (placebo). The goal was to investigate the effect of oral collagen intake on activity-related joint pain in athletes who had no evidence of pre-existing joint disease. After 24 weeks of treatment, the data was analyzed and it was found that the collagen group had statistically significant improvement in joint pain at rest, while walking, lifting weights, running, and changing direction. Based on these results, the researchers suggested that "athletes consuming collagen hydrolysate can reduce parameters (such as pain) that have a negative impact on athletic performance."


1) A double-blind, placebo-controlled, randomized, clinical study on the effectiveness of collagen peptide on osteoarthritis.

2) 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain.


Please note: We are not doctors, and cannot recommend whether you should or should not take any product. The information shared on this page is for informational purposes only and we advise consulting with your physician before taking any nutritional or dietary supplement.

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